research center for study of gene structure and function

EXCEED THE SPACE PROVIDED. Microbes responsible for infectious disease outbreaks – from either natural, e.g., multidrug-resistant Staphylococcus aureus, or bioterrorism, e.g.,anthrax, causes – are typically virulent forms of a single species.

Population genomics, which is the study of intraspecific variations of a single microbial species, is therefore a key to uncovering virulence factors and disease-causing mechanisms, as well as tracking the sources of microbial disease. The Evolutionary Informatics Lab at Hunter College is a vital partner in a multi- institutional team of comparative genomics of Borrelia burgdorferi, the Lyme disease agent.

We are responsible for the bioinformatics system development and evolutionary statistical analysis, including experimental design, data processing and warehousing, and evolutionary analysis. Through evolutionary statistical analysis our lab discovered a surprisingly high amount of genetic exchange and plasmid transfer in B. burgdorferi. To continue our success in characterizing the population structure of pathogenic bacteria based on comparative genomics, I propose a 5-years project to develop a bioinformatics infrastructure dedicated to the analysis of population variations of pathogenic microbes.

Rat Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E02A0397-96wellsplate 96 wells plate
EUR 405

Rat Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A8879 96T
EUR 700
Description: ELISA

Dog Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E08A0397-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E08A0397-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E08A0397-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E07A0397-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E07A0397-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E07A0397-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A43800 96T
EUR 700
Description: ELISA

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E06A0397-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E06A0397-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E06A0397-48wellsplate 48 wells plate
EUR 280

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E06A0397-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E06A0397-96wellsplate 96 wells plate
EUR 405

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A17621 96T
EUR 700
Description: ELISA

Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E01A0397-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A0397-48wellsplate 48 wells plate
EUR 280

Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E01A0397-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A0397-96wellsplate 96 wells plate
EUR 405

Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A0116 96T
EUR 700
Description: ELISA

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E03A0397-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E03A0397-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E03A0397-48wellsplate 48 wells plate
EUR 280

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E03A0397-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E03A0397-96wellsplate 96 wells plate
EUR 405

Sheep Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E14A0397-48wellsplate 48 wells plate
EUR 280

Sheep Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E14A0397-96wellsplate 96 wells plate
EUR 405

Sheep Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A96093 96T
EUR 700
Description: ELISA

Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A61235 96T
EUR 700
Description: ELISA

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A69947 96T
EUR 700
Description: ELISA

Bovine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A78664 96T
EUR 700
Description: ELISA

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A26368 96T
EUR 700
Description: ELISA

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E04A0397-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E04A0397-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E04A0397-48wellsplate 48 wells plate
EUR 280

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E04A0397-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E04A0397-96wellsplate 96 wells plate
EUR 405

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E09A0397-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E09A0397-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E09A0397-48wellsplate 48 wells plate
EUR 280

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E09A0397-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E09A0397-96wellsplate 96 wells plate
EUR 405

Bovine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E11A0397-48wellsplate 48 wells plate
EUR 280

Bovine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E11A0397-96wellsplate 96 wells plate
EUR 405

Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E08A0397-48wellsplate 48 wells plate
EUR 280

Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E08A0397-96wellsplate 96 wells plate
EUR 405

Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A52517 96T
EUR 700
Description: ELISA

Guinea Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A35082 96T
EUR 700
Description: ELISA

Chicken Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E12A0397-48wellsplate 48 wells plate
EUR 280

Chicken Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E12A0397-96wellsplate 96 wells plate
EUR 405

Chicken Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A87390 96T
EUR 700
Description: ELISA

Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E07A0397-48wellsplate 48 wells plate
EUR 280

Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E07A0397-96wellsplate 96 wells plate
EUR 405

Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E05A0397-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E05A0397-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E05A0397-48wellsplate 48 wells plate
EUR 280

Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E05A0397-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E05A0397-96wellsplate 96 wells plate
EUR 405

AAV-293 Cell Line
CL-0019 1×10⁶ cells/vial
EUR 420
Description: Homo sapiens, Human

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (AP)
MBS6451883-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (AP)
MBS6451883-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (PE)
MBS6451893-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (PE)
MBS6451893-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (APC)
MBS6451884-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (APC)
MBS6451884-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (HRP)
MBS6451887-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (HRP)
MBS6451887-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (FITC)
MBS6451886-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (FITC)
MBS6451886-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (Biotin)
MBS6451885-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (Biotin)
MBS6451885-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 405)
MBS6451888-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 405)
MBS6451888-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 490)
MBS6451889-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 490)
MBS6451889-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 550)
MBS6451890-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 550)
MBS6451890-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 650)
MBS6451891-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 650)
MBS6451891-5x01mL 5x0.1mL
EUR 3875

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 750)
MBS6451892-01mL 0.1mL
EUR 895

Adeno Associated Virus 4 (AAV4, AAV 4, AAV-4) (MaxLight 750)
MBS6451892-5x01mL 5x0.1mL
EUR 3875

AAV-293 Cells Complete Medium
CM-0019 125mL×4
EUR 98
Description: Cell lines complete growth medium

AAV-293 Cells Complete Medium
CM-0019-125mL4 125 mL×4
EUR 98
Description: Complete Growth Medium

AAV-293 Cells Complete Medium
MBS2568545-4x125mL 4x125mL
EUR 155

AAV-1 Helper Free Packaging System
MBS169412-1Kit 1Kit
EUR 1050

AAV-1 Helper Free Packaging System
MBS169412-5x1Kit 5x1Kit
EUR 4855

AAV-1 Helper Free Packaging System
VPK-401 1 kit
EUR 688

AAV-1 Helper Free Expression System
MBS169420-1Kit 1Kit
EUR 1320

AAV-1 Helper Free Expression System
MBS169420-5x1Kit 5x1Kit
EUR 6125

AAV-1 Helper Free Expression System
VPK-410-SER1 1 kit
EUR 876

saCas9 Nuclease AAV Virus (AAV10)
K217 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV11)
K218 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

Human Adeno Associated Virus Type 1 (AAV1) ELISA Kit
MBS9376028-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Adeno Associated Virus Type 1 (AAV1) ELISA Kit
MBS9376028-48StripWells 48-Strip-Wells
EUR 550

Human Adeno Associated Virus Type 1 (AAV1) ELISA Kit
MBS9376028-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Adeno Associated Virus Type 1 (AAV1) ELISA Kit
MBS9376028-96StripWells 96-Strip-Wells
EUR 765

AAV-1 Helper Free Promoterless Expression System
MBS169428-1Kit 1Kit
EUR 1320

AAV-1 Helper Free Promoterless Expression System
MBS169428-5x1Kit 5x1Kit
EUR 6125

AAV-1 Helper Free Promoterless Expression System
VPK-411-SER1 1 kit
EUR 876

Human Adeno-Associated Virus 6 (AAV66) ELISA Kit
MBS2608539-10x96StripWells 10x96-Strip-Wells
EUR 3040

Human Adeno-Associated Virus 6 (AAV66) ELISA Kit
MBS2608539-48StripWells 48-Strip-Wells
EUR 285

Human Adeno-Associated Virus 6 (AAV66) ELISA Kit
MBS2608539-5x96StripWells 5x96-Strip-Wells
EUR 1670

Human Adeno-Associated Virus 6 (AAV66) ELISA Kit
MBS2608539-96StripWells 96-Strip-Wells
EUR 405

saCas9 Nuclease AAV Virus (AAV1)
K208 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV8)
K215 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV9)
K216 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV2)
K209 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV3)
K210 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV4)
K211 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV5)
K212 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV6)
K213 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV7)
K214 2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml
EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

AAV-1 Helper Free Bicistronic Expression System (GFP)
MBS169460-1Kit 1Kit
EUR 1320

AAV-1 Helper Free Bicistronic Expression System (GFP)
MBS169460-5x1Kit 5x1Kit
EUR 6125

AAV-1 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER1 1 kit
EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-1 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER1 1 kit
EUR 876

AAV-1 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER1 1 kit
EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2) Rep 68 Protein, His Tag
RE8-A5243 20ug
EUR 2539.7
Description: Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2) Rep 68, His Tag (RE8-A5243) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Leu 536 (Accession # P03132-1).

AAV-1 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER1 1 kit
EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-mCherry-GFP-LC3B (AAV9, 10^13vp/ml)
C3013-250μl 250 μL Ask for price

AAV1 SaCas9
78479 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV3 SaCas9
78481 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires the Heparan Sulfate Proteoglycan (HSPG) receptor for cell attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular and intracellular kinase domains of hHGFR are required for AAV3-mediated transgene expression._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV5 SaCas9
78483 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is good at mediating gene transfer into human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for both mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV6 SaCas9
78484 50 µl x 2
EUR 545
Description: Adeno-Associated Virus serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the best transduction efficiency in pancreatic beta-cells compared to other AAV serotypes. AAV6 vectors are also particularly effective in the transduction of human prostate, breast, and liver cancer cells._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV8 SaCas9
78485 50 µl x 2
EUR 545
Description: Adeno-Associated Virus serotype 8 (AAV8) was isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes. AAV8 and 9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV5 ELISA Kit
MBS539704-INQUIRE INQUIRE Ask for price

AAV1 ELISA Kit
MBS539706-5x96Tests 5x96Tests
EUR 12990

AAV1 ELISA Kit
MBS539706-96Tests 96Tests
EUR 2785

AAV5 ELISA Kit
55R-PROPRAAV5 96 tests Ask for price

AAV1 ELISA Kit
55R-PROPRAAV1 96 tests Ask for price

AAV1 ZsGreen
78443 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism._x000D_These AAV1 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and AAV1 transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV2 ZsGreen
78444 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 2 (AAV2) is the best characterized AAV serotype. Nearly all recombinant AAV serotypes utilize the AAV2 inverted terminal repeats (ITRs). AAV2 requires the expression of Heparan Sulfate Proteoglycan (HSPG) on the surface of host cells for cell binding and internalization. Of nearly all the discovered AAV serotypes, AAV2 has the best transduction efficiency in cell culture and is the best tool for in vitro studies._x000D_These AAV2 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV3 ZsGreen
78445 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires Heparan Sulfate Proteoglycan (HSPG) for cellular attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular domain and the intracellular kinase domain of hHGFR are required for AAV3-mediated transgene expression._x000D_These AAV3 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and AAV3 transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV4 ZsGreen
78446 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 4 (AAV4) contains an expanded p5 promoter region compared to either AAV2 or AAV3. The AAV4 Rep gene product shows greater than 90% homology with the Rep products of AAV2 and AAV3. AAV4 can transduce human, monkey, and rat cells, and efficiently transduces type B astrocytes in the subventricular zone and glia overlying the rostral migratory stream neural tube._x000D_These AAV particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and AAV transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV6 ZsGreen
78448 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the best transduction efficiency in pancreatic beta-cells._x000D_These AAV6 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and AAV6 transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV8 ZsGreen
78449 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 8 (AAV8) was first isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes._x000D_These AAV8 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV9 ZsGreen
78450 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 9 (AAV9) is one of the most promising serotypes for gene therapy applications. AAV9 transduces a wide range of tissue types, including cardiac and skeletal muscles, liver, pancreas, and eye tissue. AAV9 has significantly lower seroprevalence in the human population than other AAV serotypes, making AAV9 a desirable candidate for therapeutic applications._x000D_These AAV9 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

Rat AAV9 ELISA Kit
MBS3809848-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat AAV9 ELISA Kit
MBS3809848-48StripWells 48-Strip-Wells
EUR 550

Rat AAV9 ELISA Kit
MBS3809848-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat AAV9 ELISA Kit
MBS3809848-96StripWells 96-Strip-Wells
EUR 765

AAV9 antibody
MBS533228-5mL 5mL
EUR 1030

AAV9 antibody
MBS533228-5x5mL 5x5mL
EUR 4490

AAV2 antibody
MBS530101-005mg 0.05mg
EUR 1430

AAV2 antibody
MBS530101-5x005mg 5x0.05mg
EUR 6280

AAV9 Antibody
MBS5310995-005mg 0.05mg
EUR 1455

AAV9 Antibody
MBS5310995-5x005mg 5x0.05mg
EUR 6385

AAV5 antibody
MBS535096-01mg 0.1mg
EUR 480

AAV5 antibody
MBS535096-5x01mg 5x0.1mg
EUR 2010

AAV4 antibody
MBS536076-01mg 0.1mg
EUR 480

AAV4 antibody
MBS536076-5x01mg 5x0.1mg
EUR 2010

AAV2 antibody
MBS530460-005mg 0.05mg
EUR 1305

AAV2 antibody
MBS530460-5x005mg 5x0.05mg
EUR 5725

AAV5 antibody
MBS831015-005mg 0.05mg
EUR 1395

AAV5 antibody
MBS831015-5x005mg 5x0.05mg
EUR 6120

AAV8 antibody
MBS833332-5mL 5mL
EUR 870

AAV8 antibody
MBS833332-5x5mL 5x5mL
EUR 3755

AAV8/9 antibody
MBS834190-5mL 5mL
EUR 865

AAV8/9 antibody
MBS834190-5x5mL 5x5mL
EUR 3750

AAV5 antibody
MBS834839-025mL 0.25mL
EUR 1405

AAV5 antibody
MBS834839-5x025mL 5x0.25mL
EUR 6185

AAV4 antibody
MBS830663-005mg 0.05mg
EUR 1410

AAV4 antibody
MBS830663-5x005mg 5x0.05mg
EUR 6205

AAV4 antibody
MBS830506-INQUIRE INQUIRE Ask for price

AAV9 antibody
10R-2483 5 mL Ask for price

AAV9 antibody
10R-2483S 50 ug Ask for price

AAV2 antibody
10R-A140a 50 ug Ask for price

AAV5 antibody
70R-AR002 100 ug Ask for price

AAV5 antibody
20R-2587 250 uL Ask for price

AAV9 antibody
10-2852 50 ug Ask for price

AAV4 antibody
70R-AR018 100 ug Ask for price

AAV4 antibody
10R-2470 5 mL Ask for price

AAV1 antibody
10R-2473 5 mL Ask for price

AAV4 antibody
10R-2443 50 ug Ask for price

AAV5 antibody
10R-2471 5 mL Ask for price

AAV8 antibody
10R-3126 100 uL Ask for price

AAV5 antibody
10R-2444 50 ug Ask for price

AAV5 antibody
10R-2472 5 mL Ask for price

AAV6 antibody
10R-2480 5 mL Ask for price

AAV2 antibody
10R-A111a 50 ug Ask for price

AAV8 antibody
10R-2418S 50 ug Ask for price

AAV8 antibody
10R-2481 5 mL Ask for price

AAV8/9 antibody
10R-2482 5 mL Ask for price

AAV1 Luciferase
78452 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase under the control of a CMV promoter.

AAV2 Luciferase
78453 50 µl x 2
EUR 545
Description: Adeno-Associated Virus serotype 2 (AAV2) is the best characterized AAV serotype. Nearly all recombinant AAV serotypes utilize the AAV2 inverted terminal repeats (ITRs). AAV2 requires the expression of Heparan Sulfate Proteoglycan (HSPG) on the surface of host for cells for binding and internalization. Of nearly all the discovered AAV serotypes, AAV2 has the best transduction efficiency in cell culture and is the best tool for in vitro studies._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase under the control of a CMV promoter.

AAV3 Luciferase
78454 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires the Heparan Sulfate Proteoglycan (HSPG) receptor for cell attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular and intracellular kinase domains of hHGFR are required for AAV3-mediated transgene expression._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV5 Luciferase
78456 50 µl x 2
EUR 545
Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is effective at mediating gene transfer into human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for both mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV6 Luciferase
78457 50 µl x 2
EUR 545
Description: Adeno-Associated Virus serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the best transduction efficiency in pancreatic beta-cells compared to other AAV serotypes. AAV6 vectors are also particularly effective in the transduction of human prostate, breast, and liver cancer cells._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV8 Luciferase
78458 50 µl x 2
EUR 545
Description: Adeno-Associated Virus serotype 8 (AAV8) was isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes. AAV8 and 9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV9 Luciferase
78459 50 µl x 2
EUR 545
Description: Adeno-Associated Virus serotype 9 (AAV9) is one of the most promising serotypes for gene therapy applications. AAV9 transduces a wide range of tissue types, including cardiac and skeletal muscle, liver, pancreas, and eye tissue. AAV8 and AAV9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy. AAV9 has significantly lower seroprevalence in the human population than other AAV serotypes, making AAV9 a desirable candidate for therapeutic applications.         _x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

We have two specific aims in this proposal. First, we will develop a novel statistical framework – non-housekeeping multilocus sequencing typing (NH-MLST) – of analyzing the bacterial intraspecific variations in a phylogenetic context, with the goal of detecting genes responsible for adaptive evolution in bacteria. Second, we will develop a computational infrastructure dedicated to the comparative genomics of closely related bacteria.

As comparative microbial sequencing becomes a standard approach for discovering virulence factors and tracing microbial outbreaks, the proposed project will provide a robust evolutionary analytical framework and an efficient computational system for comparative microbial genomics.