research center for study of gene structure and function

EXCEED THE SPACE PROVIDED. Microbes responsible for infectious disease outbreaks – from either natural, e.g., multidrug-resistant Staphylococcus aureus, or bioterrorism, e.g.,anthrax, causes – are typically virulent forms of a single species.

Population genomics, which is the study of intraspecific variations of a single microbial species, is therefore a key to uncovering virulence factors and disease-causing mechanisms, as well as tracking the sources of microbial disease. The Evolutionary Informatics Lab at Hunter College is a vital partner in a multi- institutional team of comparative genomics of Borrelia burgdorferi, the Lyme disease agent.

We are responsible for the bioinformatics system development and evolutionary statistical analysis, including experimental design, data processing and warehousing, and evolutionary analysis. Through evolutionary statistical analysis our lab discovered a surprisingly high amount of genetic exchange and plasmid transfer in B. burgdorferi. To continue our success in characterizing the population structure of pathogenic bacteria based on comparative genomics, I propose a 5-years project to develop a bioinformatics infrastructure dedicated to the analysis of population variations of pathogenic microbes.

Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E07A0397-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E07A0397-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E07A0397-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E08A0397-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E08A0397-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E08A0397-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A43800	BlueGene	96T	EUR 700
Description: ELISA

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E06A0397-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E06A0397-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E06A0397-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A0116	BlueGene	96T	EUR 700
Description: ELISA

Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E01A0397-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E01A0397-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A96093	BlueGene	96T	EUR 700
Description: ELISA

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E03A0397-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E03A0397-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E03A0397-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A17621	BlueGene	96T	EUR 700
Description: ELISA

Canine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A61235	BlueGene	96T	EUR 700
Description: ELISA

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A26368	BlueGene	96T	EUR 700
Description: ELISA

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E04A0397-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E04A0397-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E04A0397-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A78664	BlueGene	96T	EUR 700
Description: ELISA

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A69947	BlueGene	96T	EUR 700
Description: ELISA

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E09A0397-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E09A0397-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E09A0397-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Porcine Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A52517	BlueGene	96T	EUR 700
Description: ELISA

Guinea Pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A35082	BlueGene	96T	EUR 700
Description: ELISA

Chicken Adeno Associated Virus type 2 Antibody (AAV2-Ab) Elisa kit
E01A87390	BlueGene	96T	EUR 700
Description: ELISA

Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E05A0397-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E05A0397-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) ELISA kit
E05A0397-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Adeno Associated Virus type 2 Antibody (AAV2-Ab) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

AAV-293 Cell Line
CL-0019	Elabscience Biotech	1×10⁶ cells/vial	EUR 420
Description: Homo sapiens, Human

AAV-293 Cells Complete Medium
CM-0019-125mL4	Elabscience Biotech	125 mL×4	EUR 98
Description: Complete Growth Medium

AAV-293 Cells Complete Medium
CM-0019	Elabscience Biotech	125mL×4	EUR 98
Description: Cell lines complete growth medium

saCas9 Nuclease AAV Virus (AAV10)
K217	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV11)
K218	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

AAV-1 Helper Free Packaging System
VPK-401	Cell Biolabs	1 kit	EUR 815

AAV-1 Helper Free Expression System
VPK-410-SER1	Cell Biolabs	1 kit	EUR 1055

saCas9 Nuclease AAV Virus (AAV4)
K211	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV5)
K212	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV1)
K208	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV2)
K209	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV3)
K210	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV6)
K213	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV7)
K214	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV8)
K215	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

saCas9 Nuclease AAV Virus (AAV9)
K216	ABM	2 x 250 µl, 1 x 10^9 GC/ml, Titer: 1 x 10^9 GC/ml	EUR 375
Description: This AAV vector expresses the Cas9 orthologue from Staphylococcus Aureus (saCas9). saCas9 is ~1 kb shorter than spCas9, allowing it to be efficiently packaged in AAV Virus. Furthermore, the saCas9 enzyme recognizes a longer PAM sequence than spCas9, and thus has greater editing specificity.AAV has low immunogenicity and broad host range, making it an ideal choice for both in vivo and in vitro applications. Use this saCas9-expressing AAV virus with a target-specific saCas9-compatible sgRNA for highly specific and efficient genome editing.

AAV1 ELISA Kit
55R-PROPRAAV1	Fitzgerald	96 tests	EUR 1153
Description: ELISA kit for detection of AAV1 in the research laboratory

AAV5 ELISA Kit
55R-PROPRAAV5	Fitzgerald	96 tests	EUR 1176
Description: ELISA kit for detection of AAV5 in the research laboratory

AAV1 SaCas9
78479	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV2 SaCas9
78480	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 2 (AAV2) is the best characterized AAV serotype. Nearly all recombinant AAV serotypes utilize the AAV2 inverted terminal repeats (ITRs). AAV2 requires the expression of Heparan Sulfate Proteoglycan (HSPG) on the surface of host for cells for binding and internalization. Of nearly all the discovered AAV serotypes, AAV2 has the best transduction efficiency in cell culture and is the best tool for in vitro studies._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter. The protein contains a C-terminus HA tag.

AAV3 SaCas9
78481	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires the Heparan Sulfate Proteoglycan (HSPG) receptor for cell attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular and intracellular kinase domains of hHGFR are required for AAV3-mediated transgene expression._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV5 SaCas9
78483	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is good at mediating gene transfer into human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for both mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV6 SaCas9
78484	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the best transduction efficiency in pancreatic beta-cells compared to other AAV serotypes. AAV6 vectors are also particularly effective in the transduction of human prostate, breast, and liver cancer cells._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV8 SaCas9
78485	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 8 (AAV8) was isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes. AAV8 and 9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV9 SaCas9
78486	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 9 (AAV9) is one of the most promising serotypes for gene therapy applications. AAV9 transduces a wide range of tissue types, including cardiac and skeletal muscle, and liver, pancreas, and eye tissue. AAV8 and AAV9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy. AAV9 has significantly lower seroprevalence in the human population than other AAV serotypes, making AAV9 a desirable candidate for therapeutic applications._x000D_Cas9 is an endonuclease enzyme that introduces a double stranded break into the DNA when recruited to a specific DNA sequence by the sgRNA (single guide RNA). This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the gene._x000D_SaCas9 (Staphylococcus aureus CRISPR-associated protein 9) has demonstrated high cutting efficiency in mammalian cells, and its smaller size makes it ideal for packaging into AAV. SaCas9 recognizes a longer protospacer adjacent motif (PAM) site, 5'-NNGRRT-3', than the more traditional SpCas9 (Streptococcus pyogenes CRISPR-associated protein 9). These AAV particles constitutively express SaCas9 under the control of a CMV promoter.

AAV-1 Helper Free Promoterless Expression System
VPK-411-SER1	Cell Biolabs	1 kit	EUR 1055

AAV1 ZsGreen
78443	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism._x000D_These AAV1 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and AAV1 transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV2 ZsGreen
78444	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 2 (AAV2) is the best characterized AAV serotype. Nearly all recombinant AAV serotypes utilize the AAV2 inverted terminal repeats (ITRs). AAV2 requires the expression of Heparan Sulfate Proteoglycan (HSPG) on the surface of host cells for cell binding and internalization. Of nearly all the discovered AAV serotypes, AAV2 has the best transduction efficiency in cell culture and is the best tool for in vitro studies._x000D_These AAV2 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV3 ZsGreen
78445	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires Heparan Sulfate Proteoglycan (HSPG) for cellular attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular domain and the intracellular kinase domain of hHGFR are required for AAV3-mediated transgene expression._x000D_These AAV3 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and AAV3 transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV4 ZsGreen
78446	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 4 (AAV4) contains an expanded p5 promoter region compared to either AAV2 or AAV3. The AAV4 Rep gene product shows greater than 90% homology with the Rep products of AAV2 and AAV3. AAV4 can transduce human, monkey, and rat cells, and efficiently transduces type B astrocytes in the subventricular zone and glia overlying the rostral migratory stream neural tube._x000D_These AAV particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and AAV transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV5 ZsGreen
78447	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is good at mediating gene transfer to human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8._x000D_These AAV5 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV6 ZsGreen
78448	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the best transduction efficiency in pancreatic beta-cells._x000D_These AAV6 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and AAV6 transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV8 ZsGreen
78449	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 8 (AAV8) was first isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes._x000D_These AAV8 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

AAV9 ZsGreen
78450	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 9 (AAV9) is one of the most promising serotypes for gene therapy applications. AAV9 transduces a wide range of tissue types, including cardiac and skeletal muscles, liver, pancreas, and eye tissue. AAV9 has significantly lower seroprevalence in the human population than other AAV serotypes, making AAV9 a desirable candidate for therapeutic applications._x000D_These AAV9 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2) Rep 68 Protein, His Tag
RE8-A5243	ACROBIOSYSTEMS	20ug	EUR 2493.1
Description: Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2) Rep 68, His Tag (RE8-A5243) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Leu 536 (Accession # P03132-1).

AAV-1 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-1 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER1	Cell Biolabs	1 kit	EUR 1055

AAV9 antibody
10-2852	Fitzgerald	50 ug	EUR 957
Description: Mouse monoclonal AAV9 antibody

AAV8 antibody
10R-2418S	Fitzgerald	50 ug	EUR 778
Description: Mouse monoclonal AAV8 antibody

AAV4 antibody
10R-2443	Fitzgerald	50 ug	EUR 894
Description: Mouse monoclonal AAV 4 antibody

AAV5 antibody
10R-2444	Fitzgerald	50 ug	EUR 884
Description: Mouse monoclonal AAV 5 antibody

AAV4 antibody
10R-2470	Fitzgerald	5 mL	EUR 486
Description: Mouse monoclonal AAV 4 antibody

AAV5 antibody
10R-2471	Fitzgerald	5 mL	EUR 486
Description: Mouse monoclonal AAV 5 antibody

AAV5 antibody
10R-2472	Fitzgerald	5 mL	EUR 486
Description: Mouse monoclonal AAV 5 antibody

AAV1 antibody
10R-2473	Fitzgerald	5 mL	EUR 550.8
Description: Mouse monoclonal AAV1 antibody

AAV6 antibody
10R-2480	Fitzgerald	5 mL	EUR 549.6
Description: Mouse monoclonal AAV6 antibody

AAV8 antibody
10R-2481	Fitzgerald	5 mL	EUR 687
Description: Mouse monoclonal AAV8 antibody

AAV8/9 antibody
10R-2482	Fitzgerald	5 mL	EUR 686
Description: Mouse monoclonal AAV8/9 antibody

AAV9 antibody
10R-2483	Fitzgerald	5 mL	EUR 636
Description: Mouse monoclonal AAV9 antibody

AAV9 antibody
10R-2483S	Fitzgerald	50 ug	EUR 957
Description: Mouse monoclonal AAV9 antibody

AAV8 antibody
10R-3126	Fitzgerald	100 uL	EUR 974.4
Description: Mouse monoclonal AAV8 antibody

AAV2 antibody
10R-A111a	Fitzgerald	50 ug	EUR 917
Description: Mouse monoclonal AAV2 antibody

AAV2 antibody
10R-A140a	Fitzgerald	50 ug	EUR 1069
Description: Mouse monoclonal AAV2 antibody

AAV5 antibody
20R-2587	Fitzgerald	250 uL	EUR 908
Description: Rabbit polyclonal AAV 5 antibody

AAV5 antibody
70R-AR002	Fitzgerald	100 ug	EUR 280
Description: Affinity purified Rabbit polyclonal AAV5 antibody

AAV4 antibody
70R-AR018	Fitzgerald	100 ug	EUR 280
Description: Affinity purified Rabbit polyclonal AAV4 antibody

AAV-1 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-1 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV1 Luciferase
78452	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase under the control of a CMV promoter.

AAV2 Luciferase
78453	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 2 (AAV2) is the best characterized AAV serotype. Nearly all recombinant AAV serotypes utilize the AAV2 inverted terminal repeats (ITRs). AAV2 requires the expression of Heparan Sulfate Proteoglycan (HSPG) on the surface of host for cells for binding and internalization. Of nearly all the discovered AAV serotypes, AAV2 has the best transduction efficiency in cell culture and is the best tool for in vitro studies._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase under the control of a CMV promoter.

AAV3 Luciferase
78454	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires the Heparan Sulfate Proteoglycan (HSPG) receptor for cell attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular and intracellular kinase domains of hHGFR are required for AAV3-mediated transgene expression._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV5 Luciferase
78456	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is effective at mediating gene transfer into human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for both mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV6 Luciferase
78457	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the best transduction efficiency in pancreatic beta-cells compared to other AAV serotypes. AAV6 vectors are also particularly effective in the transduction of human prostate, breast, and liver cancer cells._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV8 Luciferase
78458	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 8 (AAV8) was isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes. AAV8 and 9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV9 Luciferase
78459	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 9 (AAV9) is one of the most promising serotypes for gene therapy applications. AAV9 transduces a wide range of tissue types, including cardiac and skeletal muscle, liver, pancreas, and eye tissue. AAV8 and AAV9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy. AAV9 has significantly lower seroprevalence in the human population than other AAV serotypes, making AAV9 a desirable candidate for therapeutic applications.         _x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

AAV1 Empty Capsids
DAGC255L	Creative Diagnostics	10 µL, 30 µL	Ask for price
Description: Recombinant

AAV5 Empty Capsids
DAGC257L	Creative Diagnostics	10 µL, 30 µL	Ask for price
Description: Recombinant

AAV6 Empty Capsids
DAGC258L	Creative Diagnostics	10 µL, 30 µL	Ask for price
Description: Recombinant

AAV8 Empty Capsids
DAGC259L	Creative Diagnostics	10 µL, 30 µL	Ask for price
Description: Recombinant

AAV1 Null Control Virus
AAV-351	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 1.

AAV2 Null Control Virus
AAV-352	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 2.

AAV3 Null Control Virus
AAV-353	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 3.

AAV4 Null Control Virus
AAV-354	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 4.

AAV5 Null Control Virus
AAV-355	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 5.

AAV6 Null Control Virus
AAV-356	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 6.

AAV1-GFP Control Virus
AAV-301	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 1.

AAV2-GFP Control Virus
AAV-302	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 2.

AAV3-GFP Control Virus
AAV-303	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 3.

AAV4-GFP Control Virus
AAV-304	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 4.

AAV5-GFP Control Virus
AAV-305	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 5.

AAV6-GFP Control Virus
AAV-306	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 6.

AAV2-Cre Control Virus
AAV-310	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 2.

AAV1-Cre Control Virus
AAV-311	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 1.

AAV3-Cre Control Virus
AAV-313	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 3.

AAV4-Cre Control Virus
AAV-314	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 4.

AAV5-Cre Control Virus
AAV-315	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 5.

AAV6-Cre Control Virus
AAV-316	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 6.

AAV2-Luc Control Virus
AAV-320	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 2.

AAV1-Luc Control Virus
AAV-321	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 1.

AAV3-Luc Control Virus
AAV-323	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 3.

AAV4-Luc Control Virus
AAV-324	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 4.

AAV5-Luc Control Virus
AAV-325	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 5.

AAV6-Luc Control Virus
AAV-326	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 6.

AAV8 Titration ELISA Kit
DEIAAV8	Creative Diagnostics	96T	EUR 624
Description: cell culture supernatants, purified virus preparations

AAV9 Titration ELISA Kit
DEIAAV9	Creative Diagnostics	96T	EUR 624
Description: cell culture supernatants, purified virus preparations

Purified AAV-6 Antibody
10R-2480AP	Fitzgerald	50 ug	EUR 811
Description: Purified Anti-AAV-6 Monoclonal Antibody

AAV1 Luciferase-eGFP
78461	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism._x000D_These AAV1 particles constitutively express the firefly (Photinus pyralis) luciferase and eGFP genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and eGFP as two separate proteins.

AAV2 Luciferase-eGFP
78462	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 2 (AAV2) is the best characterized AAV serotype. Nearly all recombinant AAV serotypes utilize the AAV2 inverted terminal repeats (ITRs). AAV2 requires the expression of Heparan Sulfate Proteoglycan (HSPG) on the surface of host cells for binding and internalization. Of nearly all the discovered AAV serotypes, AAV2 has the best transduction efficiency in cell culture and is the best tool for in vitro studies._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and eGFP genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript and expression of luciferase and eGFP as two separate proteins.

AAV3 Luciferase-eGFP
78463	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires Heparan Sulfate Proteoglycan (HSPG) for cellular attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular domain and the intracellular kinase domain of hHGFR are required for AAV3-mediated transgene expression. _x000D_These AAV3 particles constitutively express the firefly (Photinus pyralis) luciferase and eGFP genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and eGFP as two separate proteins.

AAV5 Luciferase-eGFP
78465	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is good at mediating gene transfer into human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for both mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and enhanced Green Fluorescent Protein (eGFP) genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and eGFP as two separate proteins.

AAV6 Luciferase-eGFP
78466	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the highest transduction efficiency in pancreatic beta-cells compared to other AAV serotypes._x000D_These AAV6 particles constitutively express the firefly (Photinus pyralis) luciferase and enhanced Green Fluorescent Protein (eGFP) genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and eGFP as two separate proteins.

AAV8 Luciferase-eGFP
78467	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 8 (AAV8) was first isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes. AAV8 and 9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy._x000D_These AAV8 particles constitutively express the firefly (Photinus pyralis) luciferase and enhanced Green Fluorescent Protein (eGFP) genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and eGFP as two separate proteins.

AAV9 Luciferase-eGFP
78468	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 9 (AAV9) is one of the most promising serotypes for gene therapy applications. AAV9 transduces a wide range of tissue types, including cardiac and skeletal muscle, liver, pancreas, and eye tissue. AAV8 and AAV9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy. AAV9 has significantly lower seroprevalence in the human population than other AAV serotypes, making it a desirable candidate for therapeutic applications._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and enhanced Green Fluorescent Protein (eGFP) genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript and expression of luciferase and eGFP as two separate proteins.

AAV1-LacZ Control Virus
AAV-341	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 1.

AAV2-LacZ Control Virus
AAV-342	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 2.

AAV3-LacZ Control Virus
AAV-343	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 3.

AAV4-LacZ Control Virus
AAV-344	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 4.

AAV5-LacZ Control Virus
AAV-345	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 5.

AAV6-LacZ Control Virus
AAV-346	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 6.

AAV-1 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV5 Titration ELISA Kit (Fast)
AAV-A005H	ACROBIOSYSTEMS	96tests	EUR 706.2
Description: AAV5 Titration ELISA Kit(Fast) is based on ELISA sandwich method and designed to detect and quantitative determine of AAV5 capsid titration in AAV gene therapy product preparation processing. It contains AAV5 empty capsids and a pair of antibodies against AAV5. Results are obtained by four parameter logistic curve that were parallel to the standard curves obtained. The verification results indicate that this kit can be used for the quantitative determination of AAV5 capsid titration.

AAV1 Luciferase-mCherry
78470	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and mCherry as two separate proteins.

AAV2 Luciferase-mCherry
78471	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 2 (AAV2) is the best characterized AAV serotype. Nearly all recombinant AAV serotypes utilize the AAV2 inverted terminal repeats (ITRs). AAV2 requires the expression of Heparan Sulfate Proteoglycan (HSPG) on the surface of host cells for binding and internalization. Of nearly all the discovered AAV serotypes, AAV2 has the best transduction efficiency in cell culture and is the best tool for in vitro studies._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and mCherry as two separate proteins.

AAV3 Luciferase-mCherry
78472	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 3 (AAV3) shares 82% sequence homology with AAV2, and like AAV2, requires the Heparan Sulfate Proteoglycan (HSPG) receptor for cell attachment. AAV3 vectors transduce human liver cancer cells extremely efficiently because AAV3 utilizes the human Hepatocyte Growth Factor Receptor (hHGFR) as a co-receptor for viral entry, which is highly expressed in these cells. Both the extracellular and intracellular kinase domains of hHGFR are required for AAV3-mediated transgene expression._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and mCherry as two separate proteins.

AAV5 Luciferase-mCherry
78474	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is good at mediating gene transfer into human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for both mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and mCherry as two separate proteins.

AAV6 Luciferase-mCherry
78475	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the best transduction efficiency in pancreatic beta-cells compared to other AAV serotypes._x000D_These AAV6 particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript and expression of luciferase and mCherry as two separate proteins.

AAV8 Luciferase-mCherry
78476	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 8 (AAV8) was isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes. AAV8 and 9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript and expression of luciferase and mCherry as two separate proteins.

AAV9 Luciferase-mCherry
78477	BPS Bioscience	50 µl x 2	EUR 545
Description: Adeno-Associated Virus serotype 9 (AAV9) is one of the most promising serotypes for gene therapy applications. AAV9 transduces a wide range of tissue types, including cardiac and skeletal muscle, liver, pancreas, and eye tissue. AAV8 and AAV9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy. AAV9 has significantly lower seroprevalence in the human population than other AAV serotypes, making AAV9 a desirable candidate for therapeutic applications._x000D_These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript and expression of luciferase and mCherry as two separate proteins.

AAV2 VP1, Recombinant Protein
VP1-A5143	ACROBIOSYSTEMS	500ug	EUR 321
Description: AAV2 VP1, Recombinant Protein (VP1-A5143) is expressed from E. coli cells. It contains AA Met1 - Leu735 (Accession # P03135-1).

AAV2 VP2, Recombinant Protein
VP2-A5143	ACROBIOSYSTEMS	50ug	EUR 2140
Description: AAV2 VP2, Recombinant Protein (VP2-A5143) is expressed from E. coli cells. It contains AA Met1 - Leu598 (Accession # P03135-2).

AAV2 VP3, Recombinant Protein
VP3-A5145	ACROBIOSYSTEMS	500ug	EUR 321
Description: AAV2 VP3, Recombinant Protein (VP3-A5145) is expressed from E. coli cells. It contains AA Met1 - Leu598 (Accession # P03135-3).

AAV5 (intact particle) antibody
10R-2445	Fitzgerald	50 ug	EUR 1081
Description: Mouse monoclonal AAV 5 (intact particle) antibody

AAV1 (intact particle) antibody
10R-2446	Fitzgerald	50 ug	EUR 884
Description: Mouse monoclonal AAV 1 (intact particle) antibody

AAV5 (intact particle) antibody
10R-2494	Fitzgerald	500 ul	EUR 1101.6
Description: Mouse monoclonal AAV 5 (intact particle) antibody

AAV-2 Helper Free Packaging System
VPK-402	Cell Biolabs	1 kit	EUR 815

AAV-3 Helper Free Packaging System
VPK-403	Cell Biolabs	1 kit	EUR 815

AAV-4 Helper Free Packaging System
VPK-404	Cell Biolabs	1 kit	EUR 815

AAV-5 Helper Free Packaging System
VPK-405	Cell Biolabs	1 kit	EUR 815

AAV-6 Helper Free Packaging System
VPK-406	Cell Biolabs	1 kit	EUR 815

AAV-2 Helper Free Expression System
VPK-410-SER2	Cell Biolabs	1 kit	EUR 1055

AAV-3 Helper Free Expression System
VPK-410-SER3	Cell Biolabs	1 kit	EUR 1055

AAV-4 Helper Free Expression System
VPK-410-SER4	Cell Biolabs	1 kit	EUR 1055

AAV-5 Helper Free Expression System
VPK-410-SER5	Cell Biolabs	1 kit	EUR 1055

AAV-6 Helper Free Expression System
VPK-410-SER6	Cell Biolabs	1 kit	EUR 1055

AAVancedTM Concentration Reagent (100 ml aliquot)
AAV100A-1	SBI	100 ml	EUR 462

AAVancedTM Concentration Reagent (250 ml aliquot)
AAV110A-1	SBI	250 ml	EUR 928

Rat Adeno-Associated Virus 6(AAV6) ELISA Kit
NSL0015r	Sunlong	96 Tests	EUR 498

Human Adeno-Associated Virus 2 (AAV2) ELISA Kit
abx050302-100g	Abbexa	100 µg	Ask for price

Human Adeno-Associated Virus 2 (AAV2) ELISA Kit
abx050302-200g	Abbexa	200 µg	Ask for price

Human Adeno-Associated Virus 2 (AAV2) ELISA Kit
abx050302-50g	Abbexa	50 µg	EUR 493.75

Human Adeno-Associated Virus 9 (AAV9) ELISA Kit
abx050303-100g	Abbexa	100 µg	Ask for price

Human Adeno-Associated Virus 9 (AAV9) ELISA Kit
abx050303-10g	Abbexa	10 µg	EUR 493.75

Human Adeno-Associated Virus 9 (AAV9) ELISA Kit
abx050303-50g	Abbexa	50 µg	Ask for price

pAAVK-EF1α -MCS AAVanced Cloning and Expression Vector
AAV502A-1	SBI	10 ug	EUR 614

Anti- Adeno Associated Virus 5 (AAV-5) aa530-541 Antibody
GWB-F8E71A	GenWay Biotech	0.1 mg	Ask for price

AAV-2 Helper Free Promoterless Expression System
VPK-411-SER2	Cell Biolabs	1 kit	EUR 1055

AAV-3 Helper Free Promoterless Expression System
VPK-411-SER3	Cell Biolabs	1 kit	EUR 1055

AAV-4 Helper Free Promoterless Expression System
VPK-411-SER4	Cell Biolabs	1 kit	EUR 1055

AAV-5 Helper Free Promoterless Expression System
VPK-411-SER5	Cell Biolabs	1 kit	EUR 1055

AAV-6 Helper Free Promoterless Expression System
VPK-411-SER6	Cell Biolabs	1 kit	EUR 1055

AAV-2 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER2	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-3 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER3	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-4 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER4	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-5 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER5	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-6 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER6	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-2 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER2	Cell Biolabs	1 kit	EUR 1055

We have two specific aims in this proposal. First, we will develop a novel statistical framework – non-housekeeping multilocus sequencing typing (NH-MLST) – of analyzing the bacterial intraspecific variations in a phylogenetic context, with the goal of detecting genes responsible for adaptive evolution in bacteria. Second, we will develop a computational infrastructure dedicated to the comparative genomics of closely related bacteria.

As comparative microbial sequencing becomes a standard approach for discovering virulence factors and tracing microbial outbreaks, the proposed project will provide a robust evolutionary analytical framework and an efficient computational system for comparative microbial genomics.